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B1731
Topic: Title: Testing the difference between two quantiles from independent populations Authors:  Martina Mittlboeck - Medical University of Vienna (Austria) [presenting]
Harald Heinzl - Medical University of Vienna (Austria)
Abstract: A test of the difference between two quantiles from independent populations may be based on an empirical distribution function estimator for the difference of two order statistics. Properties of this test are studied by means of a simulation study. Small to moderate sample sizes, tail quantiles and quantiles which do not coincide with the expectation of an order statistic are identified as problematic and can result in both, conservative but also extreme liberal behavior of the test. Consequently, this statistical test should be used with care for small to moderate sample sizes. This is especially true in areas of application where liberal statistical tests are usually not acceptable, like marketing authorization of medicines or medical devices.