A0473
Title: A unified framework for ROC curve inference with and without covariates
Authors: Maria Xose Rodriguez Alvarez - Universidade de Vigo (Spain) [presenting]
Abstract: A general framework is proposed for the estimation of the receiver operating characteristic (ROC) curve and its conditional counterparts, the covariate-specific ROC curve and the covariate-adjusted ROC curve. The proposal builds upon the expression of these ROC curves as the (conditional) cumulative distribution function of the so-called (conditional) placement values, i.e., the standardization of test results in the diseased population using the non-diseased population as the reference. The validity of the approach is supported by simulations and illustrated with real data.