Title: Causal inference in imaging genetics
Authors: Dehan Kong - University of Toronto (Canada) [presenting]
Abstract: Understanding the workings of human brains and their connections with dementia behaviour is a central goal in medical studies. We will introduce a new method to identify the causal relationship between hippocampal atrophy and dementia behaviour in Alzheimer disease. We consider a 2D hippocampal surface exposure and develop a causal inference procedure which can account for high dimensional potential genetic confounders. We examine the performance of our method using a large-scale imaging genetic dataset from the Alzheimer Disease Neuroimaging Initiative study.