B1347
Title: A new approximate method for Y-STR haplotype probability assignment
Authors: Jacob de Zoete - Queen Mary University of London (United Kingdom) [presenting]
Abstract: All current statistical models for the interpretation of Y-STR mixtures are hampered by a single point of failure-namely that there is no single agreed model for the assignment of Y haplotype probabilities. There are numerous competing models: the counting method, Brenners kappa method, the generalized Good method, the coalescent, the discrete Laplace, each with their strengths and weaknesses. We introduce a new approximate method, based on a Chow-Liu approximation of the dependency structure between loci. We will discuss the basis for its derivation and compare its performance to existing methods.
