A0248
Title: Challenges in measuring individual differences and reliability of brain function
Authors: Ting Xu - Child Mind Institute (United States) [presenting]
Abstract: With a growing interest in personalized medicine, functional neuroimaging research has recently shifted focus from the evaluation of group-level summaries to associating individual differences in brain function with behaviors. However, this new focus brings forth challenges related to accurately measuring the sources of individual variation in functional signals. The impact of within-individual variations is highlighted, and the concept of measurement reliability is discussed as a critical tool for accounting for within- and between-individual variations when measuring individual differences in brain function. A tool, reliability explorer (ReX), is also presented, which facilitates the examination of individual variations and reliability and the effective direction for optimizing individual differences in biomarker discovery.
