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A1180
Title: Causality-based topological ranking of brain regions during epileptic seizure Authors:  Anass El Yaagoubi Bourakna - King Abdullah University of Science and Technology (Saudi Arabia) [presenting]
Moo K Chung - University of Wisconsin-Madison (United States)
Hernando Ombao - King Abdullah University of Science and Technology (KAUST) (Saudi Arabia)
Abstract: The development of Topological Data Analysis over the last twenty years and its application to functional brain connectivity allowed neuroscientists to discover novel topological patterns in the organization of the brain. A novel TDA approach for oriented networks is proposed that intends to analyze the causality patterns in effective brain connectivity. Evidence is provided that the approach can detect causality patterns using simulated data. Furthermore, the application of this novel approach to epileptic seizure EEG data sheds light on the disruptive effect of seizures on the causal relationships between brain regions.