B0587
Title: Mediation and partial conjunction testing via p-value spacings
Authors: Kwun Chuen Gary Chan - University of Washington (United States) [presenting]
Abstract: Mediation and partial conjunction testing both have a non-convex composite null hypothesis space and traditional joint significant tests typically do not have a uniform asymptotic distribution across the null space, which results in low power for certain alternatives. By considering spacings with specific p-values, a procedure is developed that is asymptotic and non-conservative over the composite null space.
